Haskins, Mark EAguirre, Gustavo DJezyk, Peter FPatterson, Donald F2023-05-232023-05-231980-12-012013-08-19https://repository.upenn.edu/handle/20.500.14332/48932Three cats with feline arylsulfatase-B-deficient mucopolysaccharidosis were studied by light and transmission electron microscopy. Membrane-bound cytoplasmic inclusions were present in hepatocytes, bone marrow granulocytes, vascular smooth muscle cells, and fibroblasts in skin, cornea, and cardiac valves. Central nervous system lesions were restricted to mild ventricular dilatation, perithelial cell vacuolation, and, in one animal, cord compression by vertebral exostoses. The lesions in these cats closely resembled those described in human patients with mucopolysaccharidosis VI (Maroteaux-Lamy syndrome).Reproduced from Am J Pathol 1980, 101(3): 657-674 with permission from the American Society for Investigative Pathology (http://www.journals.elsevierhealth.com/periodicals/ajpa/home). The archived version of this article can also be found online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1903664/DiseasesMedicine and Health SciencesPathologyVeterinary MedicineVeterinary Pathology and PathobiologyThe Pathology of the Feline Model of Mucopolysaccharidosis VIArticle