Sidjanin, Duska JAguirre, Gustavo DMcElwee, John LMiller, Brian2023-05-232023-05-232005-06-012015-04-15https://repository.upenn.edu/handle/20.500.14332/49004We identified a pedigree of Labrador retrievers (LR) that develop hereditary cataracts between 6 and 18 months of age. In humans, galactokinase deficiency is an autosomal recessive disorder characterized by juvenile onset of cataracts.1 In order to evaluate GALK1 as a candidate gene, we cloned and sequenced the canine GALK1 gene and tested a single nucleotide polymorphism (SNP) in the gene for segregation with cataracts in the LR pedigree.This is the accepted version of the article which has been published in final form at http://dx.doi.org/10.1111/j.1365-2052.2005.01275.x.Animal DiseasesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesEye DiseasesMedical GeneticsOphthalmologyVeterinary MedicineArticle