Komáromy, András MRamsey, David TBrooks, Dennis ERamsey, Cynthia CKallberg, Maria EAndrew, Stacy E2023-05-232023-05-231999-11-012013-11-20https://repository.upenn.edu/handle/20.500.14332/48969Hemorrhage in the anterior chamber of the eye, or hyphema, results from a breakdown of the blood-ocular barrier (BOB) and is frequently associated with inflammation of the iris, ciliary body, or retina. Hyphema can also occur by retrograde blood flow into the anterior chamber via the aqueous humor drainage pathways without BOB breakdown. Hyphema attributable to blunt or perforating ocular trauma is more common than that resulting from endogenous causes. When trauma has been eliminated as a possible cause, it is prudent to assume that every animal with hyphema has a serious systemic disease until proven otherwise.Medicine and Health SciencesOphthalmologyVeterinary MedicineArticle