Brown, Lawrence DHwang, J. T. GeneMunk, Axel2023-05-232023-05-2319972016-08-10https://repository.upenn.edu/handle/20.500.14332/47595It is shown that the standard two one-sided tests procedure for bioequivalence is a biased test. Better tests exist. In this paper, an unbiased α-level test and other tests which are uniformly more powerful than the two one-sided tests procedure are constructed. Its power can be noticeably larger than that of the α-level two one-sided tests procedure.two one-sided tests procedureuniformly more powerfulpharmocokinetic parametersApplied StatisticsBiostatisticsArticle