Haskins, Mark EAguirre, Gustavo DJezyk, Peter FDesnick, Robert JPatterson, Donald F2023-05-232023-05-231983-07-012013-08-20https://repository.upenn.edu/handle/20.500.14332/48937Five cats with feline α-L-iduronidase-deficient mucopolysaccharidosis were studied. Membrane-bound cytoplasmic inclusions were present in central nervous system neurons, hepatocytes, chondrocytes, vascular and splenic smooth muscle cells, bone marrow leukocytes, and fibroblasts of the skin, eye, and cardiac valves. The lesions in these cats closely resemble those described in human patients with mucopolysaccharidosis I H (Hurler syndrome).Reproduced from Am J Pathol 1983, 112 (1): 27-36 with permission from the American Society for Investigative Pathology (http://www.journals.elsevierhealth.com/periodicals/ajpa/home). The archived version of this article can also be found online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1916323/Comparative and Laboratory Animal MedicineDiseasesMedicine and Health SciencesVeterinary MedicineThe Pathology of the Feline Model of Mucopolysaccharidosis IArticle